Department of Microbiology · Pukyong National University

Decoding fungal virulence.Designing sustainable futures.

We study the virulence mechanisms of pathogenic fungi and develop innovative biotechnologies for sustainable agriculture.

Abstract cobalt-blue data points revealing an underlying pattern
From observation to mechanism, from mechanism to action

01Integrative multi-omics

02Genome editing

03Nanotechnology

04Evolution · AI

A small researcher reading beside mushrooms and scientific monitors

Welcome to the Min Lab

Big questions, found in the microscopic world.

Fungi are crucial decomposers across the planet, yet some pathogenic fungi cause fatal infections in humans and devastating losses in crops. The emergence of antifungal resistance makes treatment and control increasingly difficult.

Through an interdisciplinary approach spanning multi-omics, genome editing, nanotechnology, and evolutionary analysis, the Min Lab investigates the molecular basis of fungal virulence and develops biotechnology that reduces agrochemical use, protects ecosystems, and supports sustainable growth.

01

Research

Three questions. One direction.

We connect fundamental discoveries in fungal virulence and evolution to technologies that protect people, plants, and ecosystems.

Ribo-seq study figure connecting yeast-to-hypha morphogenesis, uORF and alternative isoform regulation, and RNA-seq versus Ribo-seq fold changes
01

Mechanisms of virulence and drug resistance

We employ integrative multi-omics approaches to investigate novel mechanisms that promote virulence and drug resistance in pathogenic fungi. Our work reveals how the regulation of protein translation controls gene expression involved in virulence and resistance.

Detailed microneedle MXene-FET biosensor diagram showing insertion into tomato tissue and real-time ABA-dependent conductance changes
02

Nanosensors for real-time
monitoring in plants

Plants release signaling molecules to manage drought, wounds, and disease. We develop nanosensors that detect these stress-related molecules in real time, creating opportunities to mitigate stress and prevent disease while using resources more efficiently.

Detailed convolutional neural network diagram classifying more than 10,000 mushroom images by camouflage, conspicuous coloration, and white coloration
03

Exploring mushroom evolution with AI

By integrating phylogenomic data, morphological images, and ecological information, we develop AI-based models to understand how toxicity, coloration, morphology, and other traits emerged and diversified across fungal lineages.

Kyunghun Min, principal investigator of the Min Lab

Principal Investigator

Kyunghun Min

Assistant Professor · Department of Microbiology · Pukyong National University

Appointments & education

Assistant ProfessorDepartment of Microbiology, Pukyong National University
Assistant ProfessorDepartment of Plant Science, Gangneung-Wonju National University
Principal ResearcherDepartment of Agricultural Biotechnology, Seoul National University
Research ScientistRenaissance School of Medicine, Stony Brook University
Visiting ScientistDepartment of Biological Sciences, Carnegie Mellon University
Postdoctoral AssociateDepartment of Plant Pathology and Microbiology, Texas A&M University
Ph.D.Agricultural Biotechnology, Seoul National University
B.S.Applied Biology, Seoul National University

Inside the Lab

Working and growing together.

Lab Members

Graduate Students

01
Seongwon Jang portrait

Seongwon Jang

장성원

Expected B.S. · Department of Microbiology, Pukyong National University · 2026

Incoming M.S. student · Department of Microbiology, Pukyong National University · 2026

02
Jubin Kim portrait

Jubin Kim

김주빈

Expected B.S. · Department of Microbiology, Pukyong National University · 2026

Incoming M.S. student · Department of Microbiology, Pukyong National University · 2026

02

Publications

Research papers · last 10 years

* Co-first authors · † Co-corresponding authors

  1. S Bang, D Choi, S Park, S-E Lee, K Min†, S Hong†. In Vivo real-time monitoring of drought stress responses in plants using microneedle field-effect transistor biosensor. Sensors and Actuators B: Chemical. 451: 139412.

  2. K Min, A Park. Shape-shifting mechanisms: Integrative multi-omics insights into Candida albicans morphogenesis. Mycobiology. 53(2): 250–257.

  3. KA Swenson, K Min, JB Konopka. Candida albicans pathways that protect against organic peroxides and lipid peroxidation. PLoS Genetics. 20(10): e1011455.

  4. J Park, H Jeon, A Hwangbo, K Min, J Ko, J-E Kim, S Kim, JY Shin, Y-H Lee, Y-W Lee, H Son. A winged-helix DNA-binding protein is essential for self-fertility during sexual development of the homothallic fungus Fusarium graminearum. mSphere. 25(9): e0051124.

  5. H Moon*, K Min*, J Winarto, S Shin, H Jeon, DG Song†, H Son†. Proteomic analysis of cell wall proteins with various linkages in Fusarium graminearum. Journal of Agricultural and Food Chemistry. 72(11): 6028–6039.

  6. H Jeon*, JW Yang*, D Shin, D Min, BJ Kim, K Min†, H Son†. Development of a selective medium for surveillance of Fusarium head blight disease. The Plant Pathology Journal. DOI: 10.5423/PPJ.OA.12.2023.0173.

Patents

  1. Y-W Lee, AR Park, K Min, and H Son. 2012. Gibberella zeae with a deletion of FgFlbA gene and method for overproduction of mycotoxin using thereof. Korea. Patent No. 10-2012-0152584.
  2. Y-W Lee, AR Park, K Min, and H Son. 2012. A mutant substituted on GzGpa2 gene and method for production of mycotoxin using thereof. Korea. Patent No. 10-2012-0152585.

News & Events

We are looking for curious students.

We welcome students interested in pathogenic fungi and innovative biotechnology.

Watch our lab introduction

Contact

Let’s ask better questions
together.

For research collaborations, student opportunities, and inquiries about the Min Lab, please get in touch by email.

k.min@pknu.ac.kr
Min Lab · Systems Biology LaboratoryRoom 7417, Building C24, 45 Yongso-ro, Nam-Gu, Busan 48513, South Korea
Kyunghun Min, Ph.D.Room 7404, Building C24, 45 Yongso-ro, Nam-Gu, Busan 48513, South Korea
+82-51-629-5616